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As a result, AICAR reduces the frequency and size of myocardial infarcts up to 25% in humans allowing improved blood flow to the heart.

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Mandreoli and coworkers reported an 80-year-old hemodialysis patient who developed antibody-associated PRCA after 4 months of subcutaneous Eprex administration.

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Of note, in 2005 and 2006, Australia and Canada, respectively, became the first countries to reauthorize subcutaneous administration of the HSA-free formulation of Eprex, after the addition of a Teflon coating to the rubber stopper.

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